Drug Discovery

In early drug discovery open access LC/MS is widely used for compound confirmation/identification of possible drug candidates, intermediates, and other products. Enabled by unique instrument line shape calibration technology, open access LC/MS quadrupole systems can routinely achieve high mass accuracy and high spectral accuracy for the purpose of compound confirmation/identification. However, this great performance can be compromised by highly saturated MS signal caused by overly high concentration of samples. We have worked out a solution to provide open access MS users with useful results even with any data containing saturated signal and a suggested sample dilution for best possible formula confirmation/identification results.

Cerno Bioscience

Spectral Accuracy of a Saturated Peak at Different Scans

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