Introducing vendor-agnostic MS calibration software

Our breakthrough patented TrueCal™ technology enables researchers to meet the challenges associated with MS analysis – and leverage the theoretical basis of MS to achieve unprecedented accuracy.

• Calibrate MS data to a mathematically defined line shape for unsurpassed mass and spectral accuracy
• Harness the true power of MS on your existing hardware
• Eliminate backlogs and drive true confidence in lab results

A fresh take on solving old problems

Founded by scientists with deep expertise in instrumentation, data processing, and analytical software, Cerno takes an outsider approach to MS analysis. It’s a new perspective, a new technology, and a new approach to advancing the industry.

• Obtain more accurate results with MS experiments
• Achieve more with your existing hardware investments
• Works with all major MS hardware

Astrix Webinar – NSF Case Study: Accelerating GC/MS Extractables and Leachables Analysis with Advanced Software Tools

A webinar sponsored by Astrix
Date: January 8^th, 2025
Time: 1:00 PM EST / 10:00 AM PST

Presented by: Benjamin Johnson, Manager, NSF | Yongdong Wang, President, Cerno

Overview: NSF International provides services to certify the safety of drinking water equipment (NSF/ANSI 61). With 7000-8000 samples evaluated every year, the deconvolution, identification, and quantitation of Tentatively Identified Compounds (TICs) can require hours (for “clean” samples) to days (“dirty” samples) of tedious manual review from a team of four or more highly trained experts. A sample backlog of up to six months was not uncommon, and hiring and training additional analysts was a lengthy and expensive process. To complicate the problem further, multiple worldwide sites used different instrumentation, and some lacked the expertise to analyze the more complex samples.

In this webinar, we will explore:

• Why vendor-neutral software solutions are vital for global operations.
• How analysis tools should be as easy to learn and automate as possible to reduce training costs and minimize human error.
• Understand why simplifying and automating the expertise needed for review and interpretation is essential to lessen reliance on scarce and costly experienced analysts.
• Why LIMS interfacing must be flexible, easy to implement, and robust.

Featured

Whether you are new here to explore Cerno or delve into fascinating scientific topics, we regularly showcase the latest and greatest. This week’s focus is on spectral libraries, which are made available through our partnership with NIST. Additionally, we will delve into the concept of spectral accuracy.

This week we are attending the Allotrope Fall Connect meeting in Boston!

Keep coming back for more! Curious, have questions? Let’s connect and explore science together.

Spectral Accuracy

What is Spectral Accuracy? In the context of mass spectrometry, spectral accuracy refers to the ability of an instrument to accurately measure the mass-to-charge ratio (m/z) of ions, which is essential for identifying the chemical composition of a sample. High spectral accuracy is achieved by calibrating instruments to obtain high mass accuracy, which is typically expressed in parts per million (ppm). Spectral accuracy is an important measure of the accuracy of a spectral method in approximating the solution of a differential equation, and it is also a critical aspect of mass spectrometry, where it refers to the ability of an instrument to accurately measure the mass-to-charge ratio of ions.

• Spectral Accuracy Defined
• Learn About Spectral Accuracy (Analytical Chemistry Feature Article)
• Cerno Calibration Tutorial (Video)
• Spectral Accuracy to Differentiate Elemental Composition (Animation)

eFluorination using cheap and readily available tetrafluoroborate salts

Abstract: A practical electrochemical method for the rapid, safer, and mild synthesis of tertiary hindered alkyl fluorides from
carboxylic acids has been developed without the need for hydrofluoric acid salts or non-glass reactors. In this anodic fluorination,
collidinium tetrafluoroborate acts as both the supporting electrolyte and fluoride donor. A wide range of functional groups has been
shown to be compatible, and the possibility of scale-up using flow electrochemistry has also been demonstrated.

Spectral Libraries

Cerno is an authorized distributor of all NIST and Wiley libraries available making over 1,000,000 unique compounds available at great prices! New! NIST23 is now available in Agilent PBM format. Obtain more accurate results with MS experiments. Contact us for a quote for new libraries or upgrades.