Agilent Press Release

Calibration Software Enables Single Quadrupole Instruments to Easily Identify Unknowns

Cerno Bioscience and Agilent Technologies Inc. (NYSE: A) today announced they will jointly market Cerno’s MassWorks calibration software to Agilent GC/MSD ChemStation users. This novel calibration increases the mass accuracy of Agilent’s single quadrupole GC/MSD sufficiently to identify unknown compounds. This normally requires use of much more expensive, larger instruments such as Quadrupole Time-of-Flight, or Fourier Transform Ion Resonance mass spectrometers.

MassWorks for GC/MSD uses Cerno’s patented technology to calibrate raw MS data from Agilent’s GC/MSD using peak shape, followed by CLIP formula ID based on spectral accuracy. This technique dramatically improves mass accuracy and enables single-quad instruments to identify unknown compounds. In addition to enabling compound identification without a library, the formula ID function also speeds and adds confidence to library searches. The combined capabilities of the Agilent GC/MSD Chemstation and Cerno’s MassWorks means there is now an economic alternative to high-resolution GC/MS systems for formula ID.

“The combination of Agilent’s GC/MS with Cerno’s MassWorks holds real value for end users,” said Chris Toney, Agilent vice president and general manager, Mass Spec Systems. “Customers can use their workhorse single-quad instruments to identify unknowns rather than rely on more specialized instruments with associated costs and delays.”

“We’re delighted to enter into this relationship with Agilent, a recognized market leader in GC/MS. With Agilent’s large install base and worldwide reach, we will be able to make MassWorks available to many more users,” said Dr. Yongdong Wang, founder and president of Cerno Bioscience. “By configuring and pricing MassWorks specifically for the GC/MS market, we can make this solution more attractive for all GC/MS laboratories.”

MassWorks is compatible with Agilent 5975 and 5973 GC/MS instruments running Agilent MSD ChemStation software. To determine compatibility with older systems, please contact Cerno or Agilent.

More information about the Agilent GC/MSD System is available at

For more information about MassWorks for GC/MS software, please visit

About Cerno Bioscience Products

Cerno Bioscience’s MassWorks family of software products performs post-acquisition MS calibration and formula determination through either CLIPS at unit mass resolution or sCLIPS at higher resolution. It supports all major MS vendor data formats and works with all MS instruments including GC/MS, LC/MS, TOF, qTOF and FT MS. Cerno Bioscience products are used in major R&D; labs in the pharmaceutical, food, beverages, flavors, fragrances, natural products, environmental, forensics, fine chemicals and petrochemical industries. For more information, please visit:

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is the world’s premier measurement company and a technology leader in communications, electronics, life sciences and chemical analysis. The company’s 18,000 employees serve customers in more than 110 countries. Agilent had net revenues of $5.8 billion in fiscal 2008. Information about Agilent is available on the Web at

About Cerno Bioscience

Cerno is dedicated to the practical application of modern mathematical techniques to Mass Spectrometry for the purpose of improving the quality, accuracy and reliability of MS analysis. These techniques can be used to dramatically improve the amount of information obtainable from and reduce the amount of time required of many MS experiments. Cerno’s technologies are proprietary and protected through numerous patents granted and submitted world-wide. For more information on Cerno MS technologies/applications/products please visit our Web site:

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Valerie Lopez, Cerno Bioscience
+1 203 312 1106

Stuart Matlow, Agilent
+ 1 408 553 7191