Natural products have played a significant role in pharmacotherapy for cancer and infectious diseases. However, the technical barriers to screening, isolation, characterization, and optimization have made pursuing natural products for drug discovery challenging. This resulted in a decline in the pharmaceutical industry’s interest in natural products from the 1990s onwards. Natural product-based drug discovery is becoming more feasible thanks to recent technological and scientific advancements, including improved analytical tools and microbial culturing advances. There is a growing interest in using natural products as drug leads, particularly in the fight against antimicrobial resistance.
Please check out our additional resources below:
- Cerno BioscienceD. Kuehl, Y. Wang, S. Simonoff ASMS 2023
- Cerno BioscienceD. Kuehl, Y. Wang, S. Simonoff ASMS 2023
- Cerno BioscienceD. Kuehl, Y. Wang, S. Simonoff ASMS 2022
- Cerno BioscienceD. Kuehl, S. Simonoff, Y. Wang ASMS 2022
- An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis | See Supporting Information | Article referenced in Headline News!Journal of Natural ProductsShibdas Banerjee, Elumalai Gnanamani, Stephen R. Lynch, Fernando Zamudio Zuñiga, Juana María Jiménez-Vargas, Lourival Domingos Possani, and Richard N. Zare (see supporting information)
- Michigan State UniversityZ.Wang,A.Jones,Y.Wang ASMS2015