June 3, 2024

FOR IMMEDIATE RELEASE:

Cerno Bioscience Unveils New Suite of Mass Spectrometry Software Solutions

Media Contact:
Michelle C. Sharron
Vice President of Marketing
Cerno Bioscience
1180 N Town Center Dr, Suite 100
Las Vegas, NV 89144
Email: marketing@cernobioscience.com

Cerno Bioscience Unveils New Suite of Mass Spectrometry Software Solutions

LAS VEGAS, Nevada (June 2, 2024) – Cerno Bioscience will unveil a new suite of vendor-neutral mass spectrometry software solutions at ASMS booth #229, June 2-6, 2024, Anaheim, California. SAMMI™ (for Spectrally Accurate Modeling of Multiply charged Ions), an entirely new approach for analyzing any large molecule, including peptides, oligos, and proteins, the new GC/ID™ Version 5.0 software for GC/MS, which Accelerates Unknown Compound Identification and the latest version of its award-winning MassWorks™ Version 7.0 mass spectrometry research grade software.

Cerno will showcase SAMMI, a revolutionary new tool for large-molecule analysis that provides a 30X improvement in large-molecule characterization. SAMMI can confirm sequences/formulas, including multiple modifications and isotope labels, regardless of the molecule size. Users can expect 10-50X improvements in mass accuracy on single or triple quadrupole instruments.

GC/ID is a fully automated and vendor-agnostic software to achieve the most comprehensive identification beyond GC/MS Library Search, a powerful market-first solution. GC/ID accelerates the unknown ID workflow and dramatically improves the confidence of results. Featuring many innovative technologies, including patented “Full Spectrum” deconvolution and a powerful “Composite Scoring” system combining Library Search, Retention Index, and Accurate Mass (on quadrupoles). This provides for more accurate and confident unknown identification over solutions relying solely on Library Search scores.

MassWorks 7.0 is an easy-to-use post-acquisition software solution to achieve high mass accuracy and high spectral accuracy. This research-grade software provides the most advanced tools for unknown formula ID on both low and high-resolution MS instruments. Users can expect high mass accuracy on quadrupole GC or LC/MS (up to 0.005Da) and improved spectral accuracy on all systems up to 99.9%. MassWorks provides direct and accurate analysis of unresolved mixtures, e.g., isotope labeling and biologics modifications.  

Cerno will give two ASMS poster presentations. on Wednesday, June 5th, in partnership with Agilent Technologies, “Accurate mass spectral deconvolution of multiply-charged oligonucleotides using unit resolution single quadrupole LC/MS.” Followed by Thursday, June 6th, “Reducing the Pain Point of GC Retention Index Calibration for Enhanced GC/MS Compound Identification”.

For more information, please contact Cerno Bioscience at marketing@cernobioscience.com, call +1 203-312-1150, or visit www.cernobioscience.com.

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About Cerno Bioscience

For over 20 years, our passion has been developing advanced mass spectrometry software technology to dramatically improve the accuracy of MS data.  Our patented and proprietary technologies enable our customers to accelerate their workflows and reduce costs while providing more confident answers.

For the first time, we can now accurately correct the MS signal to enable new solutions for more confident analysis of both small and large molecules.  The analysis of complex mixtures such as labeled isotopes, large molecule adducts, and various modifications are easily and confidently unraveled and quantified.  The technology applies to all MS instrumentation, from routine benchtops to state-of-the-art high-resolution instruments.

Copyright 2024 Cerno Bioscience LLC. All rights reserved. Cerno Bioscience is a registered trademark and MassWorks, SAMMI, GC/ID, are trademarks of Cerno Bioscience

February 24-28, 2024

Cerno Bioscience will attend the upcoming Pittcon 2024 Conference and Exhibition on  February 24-28  in San Diego, CA, Booth #2922. Cerno will be giving some exciting presentations on new areas of research and product development, including:

2/26/2024 Press Release: Cerno Bioscience GC/MS Software Accelerates Unknown Compound Identification at Pittcon with GC/ID Version 5.0

2/27/2024 Press Release: Cerno Bioscience Unveils New Suite of Mass Spectrometry Software Solutions

DemoZone | Retention Index Made Easy for GC/MS Unknown Compound ID (Download PDF)
Monday, February 26, 2024 4:00 PM
Unknown compound analysis is an important part of science that has been around for many years. To identify a compound, we can use many different tools. Some of these key tools include GC/MS. The process of unknown compound identification (ID) can be grueling, and retention index (RI) has been shown to provide valuable additional and, oftentimes, much-needed orthogonal information. Unfortunately, accurate RI calibration in practice usually requires multiple steps, such as separate external standard (e.g., alkane series) injection and repeated injection whenever the temperature programming changes. To make matters worse, most software tools that come with commercial GC/MS systems are either tedious to use or involve manual steps. This show-and-tell demo will demonstrate an easy and seamless way for GC/MS unknown compound ID by combining spectral library search with automated retention index generation (AutoRI). This could even be accomplished without the need for a separate set of RI calibration standards or a separate injection step. By validating the library search via both forward and reverse search and then eliminating incorrect matches using a graphical RI trend model, we can generate the RI values for all GC peaks in a run automatically with high confidence, as long as there are enough number of compounds that could be confidently identified from the sample run itself. We will show how Auto RI compared to conventional RI using numerous examples, e.g., extractables and leachables (E&L) analysis, flavor and fragrances, and natural products, including essential oils

“Accelerating the GC/MS Workflow for Non-Target Analysis” (Download PDF)
Tuesday, February 27, 2024 11:00 AM to 11:20 AM · 20 min. (America/Vancouver) | Room 30C

“Improving Intact Mass Analysis of Large Molecules with Single Quadrupole MS through Spectrally Accurate Charge Deconvolution” (Download PDF)
Tuesday, February 27, 2024 4:00 PM to 4:20 PM · 20 min. (America/Vancouver) | Room 30E

December 13, 2023

FOR IMMEDIATE RELEASE: GC/ID Version 5.0
Cerno Bioscience GC/MS Software Accelerates Unknown Compound Identification

Read full press release: CernoBioscienceGCID5.0

November 2-3, 2023

Cerno Bioscience is once again proud to sponsor the upcoming Extractables & Leachables West 2023 conference, November 2-3 in La Jolla, CA.  Stay tuned for more information!

https://www.pharmaedresources.com/event/extractables-leachables-summit-west-2023/

March 18-22, 2023

Cerno Bioscience will be attending the upcoming ASMS 2023 Conference and Exhibition on June 4-8 in Houston, Booth #427.   We have some exciting new products to show including SAMMI, an entirely new approach for analyzing any large molecule including peptides, oligos, and proteins.  Here are some papers and demos you may be interested in:

“Extending the Concept of Spectral Accuracy to the Deconvolution of Multiply Charged Large Molecules”“, Poster TP 524 Tuesday June 6.

“A Novel Method for Automatically Calibrating GC Retention Index from MS Library Search Results“, Oral ThOH Thursday June 8, 3:50pm: Informatics: Innovations General Assembly C.

“Leveraging Python for Extending the Capability of MS Software Applications“, Poster MP 391 Monday June 5.

March 18-22, 2023

Cerno Bioscience will be attending the upcoming Pittcon 2023 Conference and Exhibition on  March 18-22  in Philadelphia, PA, Booth #2113.    Cerno will be giving some exciting presentations on new areas of research and product development including:

“Using Automated Retention Index and Library Search to Improve Unknown Compound ID with GC/MS”
Oral Session C17-02 8:50AM Mon, March 20 , 8:50am Room 118B

“Searching Mass Spectral Library to Solve Mixture Deconvolution Problem for GC/MS Unknown Analysis”
Oral Session C17-03 9:10AM Mon, March 20 , 8:50am Room 118B

Also, come see us in the exhibit hall at the DemoZone and LearningLab areas for these informative presentations:

DemoZone: Tuesday at 4PM “Retention Index Made Easy for GC/MS Unknown Compound ID”

LearningLab: Wednesday at 12PM “MS Software to Learn Isotopes, Isotope Distribution, and Elemental Composition Determination”

January 7, 2023

GC/ID Version 4.0 has been released.  Read about this exciting product which can make quick work of  positive compound ID on single quad systems.

June 5-9, 2022

Cerno Bioscience will be attending the upcoming 70th Annual ASMS Conference on Mass Spectrometry June 5-9  in Minneapolis, MN, Booth #527.    Cerno will be giving some exciting presentations on new areas of research and product development including:

“Direct Determination of Elemental Isotope Abundance Ratios Using Spectral Accuracy with Single Quadrupole MS Systems”
Poster MP 459, Mon, Jun 06, 10:30am – 2:30pm (Central)

“Leveraging MS Search, Accurate Mass, and Retention Index Data with a Novel User Interface to Accelerate Qualitative GC/MS Sample Review”
Poster TP 141, Tue, Jun 07, 10:30am – 2:30pm (Central)

July 7, 2020

GC/ID Version 3.0 has been released.  Read about this exciting product which can make quick work of  positive compound ID on single quad systems.

Oct 31- Nov 4 2021

Cerno Bioscience will be attending the upcoming 69th Annual ASMS Conference on Mass Spectrometry Oct 31 – Nov 4  in Philadelphia, PA Booth 614.    Cerno will be giving some exciting presentations on new areas of research and product development including:

“Accurate Mass Profile Mode GC/MS Libraries: An Investigation into Alternative Search Strategies“, Oral Room 114 Mon Nov 1, 3:50 – 4:10PM EST.

“Full Spectral Confirmation of Multiply Charged RNA Molecules and Their Modifications with a Single Quadrupole LC/MS System“, Poster ThP 239 Thurs Nov 4, 10:30AM – 2:30PM EST.

July 7, 2020

GC/ID Version 2.0 has been released.  Read about this exciting product which can make quick work of  positive compound ID on single quad systems. See full Press Release.

July 7, 2020

MassWorks Version 6.1 has been released.  Read about the flagship software that dramatically improves formula ID for any Mass Spectrometer. See full Press Release.

June 1-5, 8-12 2020

ASMS 2020 Reboot – virtual conference.  Cerno Bioscience will be manning or Virtual Booth on Friday, June 5th from 1 – 5 PM EST.  Email us to request an invitation to “Zoom in” to learn about our exciting new product release, see live demos, and chat with us and your peers to ask questions and discuss your applications.

March 11, 2020

Cerno Bioscience is now an official distributor of both the NIST and Wiley MS libraries making us the one-stop-shop for all your MS library needs.  NIST20 is the affordable standard library that includes search software and over 300,000 compounds.  Wiley libraries are the largest available and include the Wiley Registry of almost 1,000,000 compounds plus a number of specialty libraries for drugs, pesticides, flavors and fragrances, and others.     Cerno’s own MassWorks Rx GC/ID works seamlessly with both NIST and Wiley libraries for the ultimate qualitative answer machine (NIST format only).

March 1 – March 5, 2020

Cerno Bioscience will be exhibiting at Pittcon2020 in Chicago, IL.  Stop by and visit us at Booth #4019 to see our revolutionary Next Generation software applications and learn how it can help solve your most difficult problems as well as save you time and money. Cerno will be presenting 2 papers a posters and a giving alive software demo of our new GC/ID Verson 1.1 software.

The Concept of Effective Mass Accuracy for Unknown Identification – Sun Mar 1, Poster, 1:30-7:30PM Skyline Ballroom 6-2-6P

Integrating Accurate Mass, Retention Time, Deconvolution, and Library Search for Fully Automated GC/MS Essential Oil Analysis – Mon, Mar 2, Oral, 2:10pm, W175B

Live Demo – Automated and Highly Accurate GC/MS Identification of Essential Oils, Cannabis, and Extractables/Leachables – Wed Mar 4, Demo, 11:30am, Booth 1829 “Demo Zone II”

Adding Accurate Mass Identification to LC/MS Triple Quadrupole System for Cannabis Analysis – Thurs, Mar 5, Oral, 4:05pm, W181B

June 19, 2019 11am EDT

Cerno Bioscience in partnership with LCGC will be presenting an on-demand webcast titled:

“An Automated Software Solution for Highly Confident GC/MS Compound ID”

Learn how to dramatically improve your single quad GC/MS compound identification results.  To register and find out more click here.

June 2-7, 2019

Cerno Bioscience will be presenting four posters at ASMS 2019 along with partners Agilent Technologies, Activated Research Company, and New York Institute of Technology in Atlanta, GA.

A Direct Computational Approach to the Analysis of Multiply Charged Biomolecules and Their Modifications with Electrospray Mass Spectrometry –  Tuesday June 4, Poster TP 662 (New York Institute of Technology)

Screening CBD Oil Pet Supplements for Mycotoxins using LC-MS Quadrupole System with Accurate Mass Calibration  – Wednesday June 5, Poster WP 173 (Agilent Technologies)

Improving GC/MS Library Search on a Single Quadrupole Using Complementary and Orthogonal Metrics Within the Run – Wednesday June 5, Poster WP 313 (Cerno Bioscience)

Automated and Simultaneous Identification and Quantification in Extractables and Leachables Analysis – Wednesday June 5, Poster WP 478 (Activated Research Company)

April 12, 2019

MassWorks was a key tool in the ability to identify novel new alkaloids from scorpion venom that have promise in the discovery of novel new pharmaceuticals.  Read the news in c&en or see the published article in Journal of Natural Products.

June 2-6, 2019

Cerno Bioscience will be exhibiting at ASMS 2019 in Atlanta, GA. Stop by and visit us at Booth #909 to see our new software applications for the accurate characterization of biologics and impurities, and GC/ID for improving your GC/MS qualitative analysis throughput.

Cerno will demonstrate our new direct approach to the interpretation and analysis of multiply charged biomolecules which avoids the artifact-prone multiple charge deconvolution step.  This ground breaking software eliminates the uncertainties of other approaches and provides quantitative information on impurities as well.

GC/ID is fully automated and can process an entire run including NIST search, accurate mass molecular ion and fragment ID, retention time index calculation and report generation.  GC/ID also introduces a revolutionary, automated peak mixture detection and deconvolution algorithm which can help solve your most difficult problems as well as save you time and money.

MassWorks 5.0 will also be exhibited.  The vendor neutral desktop application enables Formula ID on conventional quadrupole LC and GC systems by improving the mass accuracy to +/- 5mDa and Spectral Accuracy to >99%.  Cerno will also be demonstrating it’s mixture deconvolution software enabling accurate analysis of impurities and degradants for both large and small molecules on both low and high resolution instruments.

March 17 – March 21, 2019

Cerno Bioscience will be exhibiting at Pittcon2019 in Philadelphea, PA.  Stop by and visit us at Booth #3927 to see our revolutionary Next Generation software applications and learn how it can help solve your most difficult problems as well as save you time and money. Bioscience will be presenting a paper and two posters and a live software demo.

Accurate Mass Confirmation/Identification for Organic Synthesis with Single Quadrupole Mass Spec – Sun Mar 17 Poster. Afternoon Room Pub 220-19 P

Accurate Characterization of Biologics and Impurities by Quadrupole Mass Spectrometry and a Comparison to HiRes MS – Mon, Mar 18 Oral. 8:30am, 126A

Live Demo – Improving the Confidence of GC/MS Compound ID Using Accurate Mass and Automated Mixture Detection – Wed Mar 20 Demo 2:30pm.  Booth 3042 “Demo Zone”

A Generalized Approach to the Deconvolution of Unresolved Chromatographic Peaks in Mass Spectrometry – Thurs, Mar 21 Poster 2PM-4:30PM. Expo floor 2110-1 P

June 3-7, 2018

Cerno Bioscience will be presenting an oral presentation and a poster at ASMS 2018 in San Diego, CA.

Quadrupole GC/MS Fragment Analysis for Improving Compound Identification – Monday June 4, 9:30AM Oral, Session-GC/MS, GC/GC/MS, GC/MS/MS, AND GC/HRMS, Room – Ballroom 20D upper level.

A New Approach to the Analysis of Unresolved Chromatographic Peaks in GC/MS – Tuesday June 5, Poster – TP 816.

June 3-7, 2018

Cerno Bioscience will be exhibiting at ASMS 2018 in San Diego, CA. Stop by and visit us at Booth #721 to see our revolutionary Next Generation software applications, MassWorks Rx and MassWorks Rx GC/ID.

Rx is a powerful, configurable software platform for automated MS data processing using Cerno’s award winning, patented calibration technologies.  GC/ID is built on the Rx platform which dramatically improves GC/MS compound identification.

GC/ID is fully automated and can process an entire run including NIST search, accurate mass molecular ion and fragment ID, and report generation.  GC/ID also introduces a revolutionary, automated peak mixture detection and deconvolution algorithm which can help solve your most difficult problems as well as save you time and money.

MassWorks 5.0 will also be exhibited.  The vendor neutral desktop application enables Formula ID on conventional quadrupole LC and GC systems by improving the mass accuracy to +/- 5mDa and Spectral Accuracy to >99%.  Cerno will also be demonstrating it’s mixture deconvolution software enabling accurate analysis of impurities and degradants for both large and small molecules on both low and high resolution instruments.

February 26 – March 1, 2018

Cerno Bioscience will be presenting two papers and two posters at Pittcon2018 in Orlando, Florida.

A Universal Work Flow Automation Toolbox for Mass Spectrometry – Sunday Feb 25 Poster.  3:30-7:30pm Valencia Ballroom D, W415

Accurate Mass Identification of Pharmaceutical Impurities and Degradants with Single Quad LCMS – Monday Feb 26 Oral. 10:25 – 10:45am,  308D

An Automated System for Validating and Enhancing GC/MS Library Search – Thu, Mar 01 Poster.  10:00am-12:00pm Exposition Floor, Aisles 2000-2700,1910-4

A Robust Method for Ultra-High Resolution MS Elemental Composition Determination – Thu, Mar 01 Oral.  4:05-4:25pm 308A,
2110-9

February 26 – March 1, 2018

Cerno Bioscience will be exhibiting at Pittcon2018 in Orlando, Florida.  Stop by and visit us at Booth #2223 to see our revolutionary Next Generation software applications and learn how it can help solve your most difficult problems as well as save you time and money.

June 5, 2017

Agilent Technologies announces availability of Cerno Bioscience MassWorks bundled with the new InfinityLab Series LC/MSD single quadrupole MS (see press release here).  Learn more on the Agilent website and review the Agilent application note and the Agilent brochure.

June 13, 2017
11 am EDT
8 am PDT
4 pm BST
5 pm CEST

Cerno Bioscience in collaboration with LCGC will be presenting a live Webcast titled: “The Application of Spectral Accuracy to Mass Spectrometry for Enhanced Formula ID and Mixture Analysis”

Sign up today!

June 4-8, 2017

Cerno Bioscience will be exhibiting at ASMS2017 in Indianapolis, Indiana, booth #628.  Stop by and visit us.  Cerno will also be presenting 2 joint posters:

WP 399 – Direct and Accurate LC/MS Quantitation of Ring Labeled Compounds

WP 654 – Determination of Ligand Number and Distribution in Intact Protein Conjugates with High Mass MALDITOF-MS

April 28, 2017

Cerno is now shipping MassWorks Version 5.0.  Dozens of new features including NIST Library search integration, complex mixture analysis, and much, much, more!