TrueFit™ allows the deconvolution chromatographically unresolved compounds commonly encountered in labeled isotope work, protein or oligonucleotide modifications, electron impact MS, or even for the direct analysis of complex mixtures.  Only Cerno makes such challenging applications routine using the patented TrueCal™ calibration technology and the subsequent application of the CLIPS and sCLIPS multivariate mixture fitting.

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The figure above illustrates the direct quantitation of a 14C labeled compound involving aromatic ring.