April 18-19, 2024
Cerno Bioscience is once again proud to sponsor the upcoming Extractables & Leachables East 2024 conference, April 18-19 in Philadelphia, PA. Stay tuned for more information!
April 24, 2024—It was great connecting with everyone at the PharmEd Extractables and Leachables event last week!
Let’s stay connected and feel free to download the NSF Case Study Presentation “Accelerating GC/MS E&L Analysis with Advanced Software Analysis Tools“.
Click here to learn more about Cerno’s GC/ID vendor-neutral software solution that enhances the performance of your GC/MS library search and compound identification process.
June 2-6, 2024
Cerno Bioscience will attend the upcoming ASMS 2024 Conference and Exhibition on June 2-6 in San Diego, California Booth #229. We have some exciting new products to show, including SAMMI, an entirely new approach for analyzing any large molecule, including peptides, oligos, and proteins.
Wednesday, June 5 | LC/MS: Chromatography and Software
Abstract ID number: 317165 – Abstract title: Accurate mass spectral deconvolution of multiply-charged oligonucleotides using unit resolution single quadrupole LC/MSThursday, June 6 | GC/MS: Instrumentation and ApplicationsAbstract ID number: 318882: Abstract title: Reducing the Pain Point of GC Retention Index Calibration for Enhanced GC/MS Compound IdentificationFebruary 24-28, 2024
Cerno Bioscience will attend the upcoming Pittcon 2024 Conference and Exhibition on February 24-28 in San Diego, CA, Booth #2922. Cerno will be giving some exciting presentations on new areas of research and product development, including:
2/26/2024 Press Release: Cerno Bioscience GC/MS Software Accelerates Unknown Compound Identification at Pittcon with GC/ID Version 5.0
2/27/2024 Press Release: Cerno Bioscience Unveils New Suite of Mass Spectrometry Software Solutions
DemoZone | Retention Index Made Easy for GC/MS Unknown Compound ID (Download PDF)
Monday, February 26, 2024 4:00 PM
Unknown compound analysis is an important part of science that has been around for many years. To identify a compound, we can use many different tools. Some of these key tools include GC/MS. The process of unknown compound identification (ID) can be grueling, and retention index (RI) has been shown to provide valuable additional and, oftentimes, much-needed orthogonal information. Unfortunately, accurate RI calibration in practice usually requires multiple steps, such as separate external standard (e.g., alkane series) injection and repeated injection whenever the temperature programming changes. To make matters worse, most software tools that come with commercial GC/MS systems are either tedious to use or involve manual steps. This show-and-tell demo will demonstrate an easy and seamless way for GC/MS unknown compound ID by combining spectral library search with automated retention index generation (AutoRI). This could even be accomplished without the need for a separate set of RI calibration standards or a separate injection step. By validating the library search via both forward and reverse search and then eliminating incorrect matches using a graphical RI trend model, we can generate the RI values for all GC peaks in a run automatically with high confidence, as long as there are enough number of compounds that could be confidently identified from the sample run itself. We will show how Auto RI compared to conventional RI using numerous examples, e.g., extractables and leachables (E&L) analysis, flavor and fragrances, and natural products, including essential oils“Accelerating the GC/MS Workflow for Non-Target Analysis” (Download PDF)
Tuesday, February 27, 2024 11:00 AM to 11:20 AM · 20 min. (America/Vancouver) | Room 30C“Improving Intact Mass Analysis of Large Molecules with Single Quadrupole MS through Spectrally Accurate Charge Deconvolution” (Download PDF)
Tuesday, February 27, 2024 4:00 PM to 4:20 PM · 20 min. (America/Vancouver) | Room 30EDecember 13, 2023
FOR IMMEDIATE RELEASE: GC/ID Version 5.0
Cerno Bioscience GC/MS Software Accelerates Unknown Compound IdentificationRead full press release: CernoBioscienceGCID5.0
November 2-3, 2023
Cerno Bioscience is once again proud to sponsor the upcoming Extractables & Leachables West 2023 conference, November 2-3 in La Jolla, CA. Stay tuned for more information!
https://www.pharmaedresources.com/event/extractables-leachables-summit-west-2023/
March 18-22, 2023
Cerno Bioscience will be attending the upcoming ASMS 2023 Conference and Exhibition on June 4-8 in Houston, Booth #427. We have some exciting new products to show including SAMMI, an entirely new approach for analyzing any large molecule including peptides, oligos, and proteins. Here are some papers and demos you may be interested in:
“Extending the Concept of Spectral Accuracy to the Deconvolution of Multiply Charged Large Molecules”“, Poster TP 524 Tuesday June 6.
“A Novel Method for Automatically Calibrating GC Retention Index from MS Library Search Results“, Oral ThOH Thursday June 8, 3:50pm: Informatics: Innovations General Assembly C.
“Leveraging Python for Extending the Capability of MS Software Applications“, Poster MP 391 Monday June 5.
March 18-22, 2023
Cerno Bioscience will be attending the upcoming Pittcon 2023 Conference and Exhibition on March 18-22 in Philadelphia, PA, Booth #2113. Cerno will be giving some exciting presentations on new areas of research and product development including:
“Using Automated Retention Index and Library Search to Improve Unknown Compound ID with GC/MS”
Oral Session C17-02 8:50AM Mon, March 20 , 8:50am Room 118B“Searching Mass Spectral Library to Solve Mixture Deconvolution Problem for GC/MS Unknown Analysis”
Oral Session C17-03 9:10AM Mon, March 20 , 8:50am Room 118BAlso, come see us in the exhibit hall at the DemoZone and LearningLab areas for these informative presentations:
DemoZone: Tuesday at 4PM “Retention Index Made Easy for GC/MS Unknown Compound ID”
LearningLab: Wednesday at 12PM “MS Software to Learn Isotopes, Isotope Distribution, and Elemental Composition Determination”
January 7, 2023
GC/ID Version 4.0 has been released. Read about this exciting product which can make quick work of positive compound ID on single quad systems.
June 5-9, 2022
Cerno Bioscience will be attending the upcoming 70th Annual ASMS Conference on Mass Spectrometry June 5-9 in Minneapolis, MN, Booth #527. Cerno will be giving some exciting presentations on new areas of research and product development including:
“Direct Determination of Elemental Isotope Abundance Ratios Using Spectral Accuracy with Single Quadrupole MS Systems”
Poster MP 459, Mon, Jun 06, 10:30am – 2:30pm (Central)“Leveraging MS Search, Accurate Mass, and Retention Index Data with a Novel User Interface to Accelerate Qualitative GC/MS Sample Review”
Poster TP 141, Tue, Jun 07, 10:30am – 2:30pm (Central)July 7, 2020
GC/ID Version 3.0 has been released. Read about this exciting product which can make quick work of positive compound ID on single quad systems.
Oct 31- Nov 4 2021
Cerno Bioscience will be attending the upcoming 69th Annual ASMS Conference on Mass Spectrometry Oct 31 – Nov 4 in Philadelphia, PA Booth 614. Cerno will be giving some exciting presentations on new areas of research and product development including:
“Accurate Mass Profile Mode GC/MS Libraries: An Investigation into Alternative Search Strategies“, Oral Room 114 Mon Nov 1, 3:50 – 4:10PM EST.
“Full Spectral Confirmation of Multiply Charged RNA Molecules and Their Modifications with a Single Quadrupole LC/MS System“, Poster ThP 239 Thurs Nov 4, 10:30AM – 2:30PM EST.
July 7, 2020
GC/ID Version 2.0 has been released. Read about this exciting product which can make quick work of positive compound ID on single quad systems. See full Press Release.
July 7, 2020
MassWorks Version 6.1 has been released. Read about the flagship software that dramatically improves formula ID for any Mass Spectrometer. See full Press Release.
June 1-5, 8-12 2020
ASMS 2020 Reboot – virtual conference. Cerno Bioscience will be manning or Virtual Booth on Friday, June 5th from 1 – 5 PM EST. Email us to request an invitation to “Zoom in” to learn about our exciting new product release, see live demos, and chat with us and your peers to ask questions and discuss your applications.
March 11, 2020
Cerno Bioscience is now an official distributor of both the NIST and Wiley MS libraries making us the one-stop-shop for all your MS library needs. NIST20 is the affordable standard library that includes search software and over 300,000 compounds. Wiley libraries are the largest available and include the Wiley Registry of almost 1,000,000 compounds plus a number of specialty libraries for drugs, pesticides, flavors and fragrances, and others. Cerno’s own MassWorks Rx GC/ID works seamlessly with both NIST and Wiley libraries for the ultimate qualitative answer machine (NIST format only).
March 1 – March 5, 2020
Cerno Bioscience will be exhibiting at Pittcon2020 in Chicago, IL. Stop by and visit us at Booth #4019 to see our revolutionary Next Generation software applications and learn how it can help solve your most difficult problems as well as save you time and money. Cerno will be presenting 2 papers a posters and a giving alive software demo of our new GC/ID Verson 1.1 software.
The Concept of Effective Mass Accuracy for Unknown Identification – Sun Mar 1, Poster, 1:30-7:30PM Skyline Ballroom 6-2-6P
Integrating Accurate Mass, Retention Time, Deconvolution, and Library Search for Fully Automated GC/MS Essential Oil Analysis – Mon, Mar 2, Oral, 2:10pm, W175B
Live Demo – Automated and Highly Accurate GC/MS Identification of Essential Oils, Cannabis, and Extractables/Leachables – Wed Mar 4, Demo, 11:30am, Booth 1829 “Demo Zone II”
Adding Accurate Mass Identification to LC/MS Triple Quadrupole System for Cannabis Analysis – Thurs, Mar 5, Oral, 4:05pm, W181B
June 19, 2019 11am EDT
Cerno Bioscience in partnership with LCGC will be presenting an on-demand webcast titled:
“An Automated Software Solution for Highly Confident GC/MS Compound ID”
Learn how to dramatically improve your single quad GC/MS compound identification results. To register and find out more click here.
June 2-7, 2019
Cerno Bioscience will be presenting four posters at ASMS 2019 along with partners Agilent Technologies, Activated Research Company, and New York Institute of Technology in Atlanta, GA.
A Direct Computational Approach to the Analysis of Multiply Charged Biomolecules and Their Modifications with Electrospray Mass Spectrometry – Tuesday June 4, Poster TP 662 (New York Institute of Technology)
Screening CBD Oil Pet Supplements for Mycotoxins using LC-MS Quadrupole System with Accurate Mass Calibration – Wednesday June 5, Poster WP 173 (Agilent Technologies)
Improving GC/MS Library Search on a Single Quadrupole Using Complementary and Orthogonal Metrics Within the Run – Wednesday June 5, Poster WP 313 (Cerno Bioscience)
Automated and Simultaneous Identification and Quantification in Extractables and Leachables Analysis – Wednesday June 5, Poster WP 478 (Activated Research Company)
April 12, 2019
MassWorks was a key tool in the ability to identify novel new alkaloids from scorpion venom that have promise in the discovery of novel new pharmaceuticals. Read the news in c&en or see the published article in Journal of Natural Products.
June 2-6, 2019
Cerno Bioscience will be exhibiting at ASMS 2019 in Atlanta, GA. Stop by and visit us at Booth #909 to see our new software applications for the accurate characterization of biologics and impurities, and GC/ID for improving your GC/MS qualitative analysis throughput.
Cerno will demonstrate our new direct approach to the interpretation and analysis of multiply charged biomolecules which avoids the artifact-prone multiple charge deconvolution step. This ground breaking software eliminates the uncertainties of other approaches and provides quantitative information on impurities as well.
GC/ID is fully automated and can process an entire run including NIST search, accurate mass molecular ion and fragment ID, retention time index calculation and report generation. GC/ID also introduces a revolutionary, automated peak mixture detection and deconvolution algorithm which can help solve your most difficult problems as well as save you time and money.
MassWorks 5.0 will also be exhibited. The vendor neutral desktop application enables Formula ID on conventional quadrupole LC and GC systems by improving the mass accuracy to +/- 5mDa and Spectral Accuracy to >99%. Cerno will also be demonstrating it’s mixture deconvolution software enabling accurate analysis of impurities and degradants for both large and small molecules on both low and high resolution instruments.
March 17 – March 21, 2019
Cerno Bioscience will be exhibiting at Pittcon2019 in Philadelphea, PA. Stop by and visit us at Booth #3927 to see our revolutionary Next Generation software applications and learn how it can help solve your most difficult problems as well as save you time and money. Bioscience will be presenting a paper and two posters and a live software demo.
Accurate Mass Confirmation/Identification for Organic Synthesis with Single Quadrupole Mass Spec – Sun Mar 17 Poster. Afternoon Room Pub 220-19 P
Accurate Characterization of Biologics and Impurities by Quadrupole Mass Spectrometry and a Comparison to HiRes MS – Mon, Mar 18 Oral. 8:30am, 126A
A Generalized Approach to the Deconvolution of Unresolved Chromatographic Peaks in Mass Spectrometry – Thurs, Mar 21 Poster 2PM-4:30PM. Expo floor 2110-1 P
June 3-7, 2018
Cerno Bioscience will be presenting an oral presentation and a poster at ASMS 2018 in San Diego, CA.
Quadrupole GC/MS Fragment Analysis for Improving Compound Identification – Monday June 4, 9:30AM Oral, Session-GC/MS, GC/GC/MS, GC/MS/MS, AND GC/HRMS, Room – Ballroom 20D upper level.
A New Approach to the Analysis of Unresolved Chromatographic Peaks in GC/MS – Tuesday June 5, Poster – TP 816.
June 3-7, 2018
Cerno Bioscience will be exhibiting at ASMS 2018 in San Diego, CA. Stop by and visit us at Booth #721 to see our revolutionary Next Generation software applications, MassWorks Rx and MassWorks Rx GC/ID.
Rx is a powerful, configurable software platform for automated MS data processing using Cerno’s award winning, patented calibration technologies. GC/ID is built on the Rx platform which dramatically improves GC/MS compound identification.
GC/ID is fully automated and can process an entire run including NIST search, accurate mass molecular ion and fragment ID, and report generation. GC/ID also introduces a revolutionary, automated peak mixture detection and deconvolution algorithm which can help solve your most difficult problems as well as save you time and money.
MassWorks 5.0 will also be exhibited. The vendor neutral desktop application enables Formula ID on conventional quadrupole LC and GC systems by improving the mass accuracy to +/- 5mDa and Spectral Accuracy to >99%. Cerno will also be demonstrating it’s mixture deconvolution software enabling accurate analysis of impurities and degradants for both large and small molecules on both low and high resolution instruments.
February 26 – March 1, 2018
Cerno Bioscience will be presenting two papers and two posters at Pittcon2018 in Orlando, Florida.
A Universal Work Flow Automation Toolbox for Mass Spectrometry – Sunday Feb 25 Poster. 3:30-7:30pm Valencia Ballroom D, W415
Accurate Mass Identification of Pharmaceutical Impurities and Degradants with Single Quad LCMS – Monday Feb 26 Oral. 10:25 – 10:45am, 308D
An Automated System for Validating and Enhancing GC/MS Library Search – Thu, Mar 01 Poster. 10:00am-12:00pm Exposition Floor, Aisles 2000-2700,1910-4
A Robust Method for Ultra-High Resolution MS Elemental Composition Determination – Thu, Mar 01 Oral. 4:05-4:25pm 308A,
2110-9February 26 – March 1, 2018
Cerno Bioscience will be exhibiting at Pittcon2018 in Orlando, Florida. Stop by and visit us at Booth #2223 to see our revolutionary Next Generation software applications and learn how it can help solve your most difficult problems as well as save you time and money.
June 5, 2017
Agilent Technologies announces availability of Cerno Bioscience MassWorks bundled with the new InfinityLab Series LC/MSD single quadrupole MS (see press release here). Learn more on the Agilent website and review the Agilent application note and the Agilent brochure.
June 13, 2017
11 am EDT
8 am PDT
4 pm BST
5 pm CESTCerno Bioscience in collaboration with LCGC will be presenting a live Webcast titled: “The Application of Spectral Accuracy to Mass Spectrometry for Enhanced Formula ID and Mixture Analysis”
June 4-8, 2017
Cerno Bioscience will be exhibiting at ASMS2017 in Indianapolis, Indiana, booth #628. Stop by and visit us. Cerno will also be presenting 2 joint posters:
WP 399 – Direct and Accurate LC/MS Quantitation of Ring Labeled Compounds
WP 654 – Determination of Ligand Number and Distribution in Intact Protein Conjugates with High Mass MALDITOF-MS
April 28, 2017
Cerno is now shipping MassWorks Version 5.0. Dozens of new features including NIST Library search integration, complex mixture analysis, and much, much, more!
March 5-9, 2017
Cerno Bioscience presenting two papers and a poster at Pittcon2017 in Chicago, Illinois. Our papers on Monday at 3:05PM room W177 (TP0740) and Wednesday at 1:30PM room W478A (TP1980). Our poster is on Sunday at 3:30-7:30PM at the Skyline Ballroom, West 375a (TP0220).
March 5-9, 2017
Cerno Bioscience will be exhibiting at Pittcon2017 in Chicago, Illinois. Stop by and visit us at Booth #3824 to discuss your application.
November 12, 2013
November 3, 2009
Cerno Bioscience, Agilent Technologies to Co-Market MassWorks for GC/MSD.